From past experience, I recommend one stud in one of the front holes. Trying to get the intake over 4 studs without scratching the mating surface is a pain. But that one stud makes a huge difference in getting the intake and gasket aligned. I pull the stud out after I get the other bolts started.
It's not something most people do very often, though, so in the end, it's not a big deal.
Personally, the only thing I think spacers are good for are taller valve covers or other valvetrain access without having to remove the upper. I think they were useful for carbs when there was fuel in the carb itself, but I don't think they're worth anything on port injection power-wise. After driving a basically stock truck again for about a thousand miles, I can say I think the last thing it needs is more torque and less revs. Plus you've added one more mating surface that just makes for one more place for a misalignment to cause turbulence.
Unless it's this spacer:
